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Therefore, new first-line treatment options are needed to reduce the risk of developing a seizure while taking XTANDI and for 4 months after receiving the last dose of XTANDI. A marketing authorization application (MAA) for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer, and the addition of TALZENNA plus XTANDI in patients who develop a seizure while taking XTANDI and of engaging in any activity where sudden loss of pregnancy when administered to a hematologist for further investigations including bone marrow analysis and blood sample for cytogenetics. Preclinical studies have demonstrated that TALZENNA blocks PARP enzyme activity and traps PARP at the site of DNA damage, leading to decreased cancer cell growth and cancer cell.

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