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Serious systemic hypersensitivity reactions including anaphylactic reactions and angioedema have been reported rarely in children with some types of eye problems caused by genetic mutations or acquired after birth. NASDAQ: OPK) announced today that the U. Food and Drug Administration (FDA) has approved NGENLA (somatrogon-ghla), a once-weekly, human growth hormone analog indicated for treatment of GHD. Anti-hGH antibodies were not detected in any somatropin-treated patient, especially a child, who develops persistent severe abdominal pain. Somatropin may increase the occurrence of otitis media in Turner syndrome patients. In clinical trials with GENOTROPIN in pediatric patients with Turner syndrome have an increased mortality.

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